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Examination unveiled that conolidine and cannabidiol significantly blocked Cav2.2 channels. While in the peripheral and central nervous system, Cav2.two channels are located predominantly at presynaptic terminals32 and Participate in essential roles in pain perception by modulating depolarization-induced calcium entry into neurons33,34. Compounds t
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Evaluation unveiled that conolidine and cannabidiol substantially blocked Cav2.2 channels. Within the peripheral and central anxious procedure, Cav2.two channels are located predominantly at presynaptic terminals32 and Participate in crucial roles in soreness perception by modulating depolarization-induced calcium entry into neurons33,34. Compounds
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